| Date | Location | Result | |
| Nov 26, 2010 | Ypsilanti, Mich. | Northern Illinois 71, Eastern Michigan 3 | Box score |
| Nov 20, 2010 | Buffalo, N.Y. | Eastern Michigan 21, Buffalo 17 | Box score |
| Nov 13, 2010 | Kalamazoo, Mich. | Western Michigan 45, Eastern Michigan 30 | Box score |
| Oct 30, 2010 | Ypsilanti, Mich. | Toledo 42, Eastern Michigan 7 | Box score |
| Oct 23, 2010 | Charlottesville, Va. | Virginia 48, Eastern Michigan 21 | Box score |
| Oct 16, 2010 | Muncie, Ind. | Eastern Michigan 41, Ball State 38 | Box score |
| Oct 09, 2010 | Nashville, Tenn. | Vanderbilt 52, Eastern Michigan 6 | Box score |
| Oct 02, 2010 | Ypsilanti, Mich. | Ohio 30, Eastern Michigan 17 | Box score |
| Sep 25, 2010 | Columbus, Ohio | Ohio State 73, Eastern Michigan 20 | Box score |
| Sep 18, 2010 | Ypsilanti, Mich. | Central Michigan 52, Eastern Michigan 14 | Box score |
| Sep 11, 2010 | Oxford, Ohio | Miami 28, Eastern Michigan 21 | Box score |
| Sep 04, 2010 | Ypsilanti, Mich. | Army 31, Eastern Michigan 27 | Box score |