| Date | Location | Result | |
| 03/05/22 | Muncie, IN | Ball St. 92, Eastern Michigan 58 | Box score |
| 03/02/22 | Kalamazoo, Mich. | Western Michigan 68, Eastern Michigan 52 | Box score |
| 02/26/22 | Ypsilanti, MI | Toledo 75, Eastern Michigan 51 | Box score |
| 02/23/22 | DeKalb, IL | Northern Ill. 72, Eastern Michigan 65 | Box score |
| 02/19/22 | Mount Pleasant, MI | Eastern Michigan 83, Central Mich. 70 | Box score |
| 02/16/22 | Ypsilanti, MI | Eastern Michigan 70, Miami (OH) 61 | Box score |
| 02/14/22 | Athens, OH | Ohio 66, Eastern Michigan 53 | Box score |
| 02/12/22 | Ypsilanti, MI | Akron 64, Eastern Michigan 53 | Box score |
| 02/09/22 | Buffalo, NY | Buffalo 93, Eastern Michigan 68 | Box score |
| 02/05/22 | Ypsilanti, MI | Kent St. 70, Eastern Michigan 61 | Box score |
| 02/02/22 | Ypsilanti, MI | Buffalo 69, Eastern Michigan 62 | Box score |
| 01/29/22 | Oxford, OH | Eastern Michigan 80, Miami (OH) 69 | Box score |
| 01/26/22 | Akron, OH | Akron 68, Eastern Michigan 64 | Box score |
| 01/24/22 | Ypsilanti, MI | Bowling Green 71, Eastern Michigan 60 | Box score |
| 01/22/22 | Ypsilanti, MI | Northern Ill. 85, Eastern Michigan 76 | Box score |
| 01/19/22 | Ypsilanti, MI | Western Michigan 62, Eastern Michigan 57 | Box score |
| 01/15/22 | Kent, OH | Kent St. 83, Eastern Michigan 58 | Box score |
| 01/12/22 | Ypsilanti, MI | Ball St. 83, Eastern Michigan 73 | Box score |
| 01/08/22 | Ypsilanti, MI | Eastern Michigan 80, Central Mich. 60 | Box score |
| 01/05/22 | Toledo, OH | Toledo 64, Eastern Michigan 48 | Box score |
| 12/10/21 | Ypsilanti, MI | Eastern Michigan 66, Binghamton 62 | Box score |
| 12/07/21 | Norman, OK | Oklahoma 94, Eastern Michigan 58 | Box score |
| 11/27/21 | Miami, FL | FIU 67, Eastern Michigan 60 | Box score |
| 11/26/21 | Miami, FL | Delaware 87, Eastern Michigan 72 | Box score |
| 11/18/21 | Ypsilanti, MI | Eastern Michigan 133, Grace Christian (MI) 45 | Box score |
| 11/13/21 | Ypsilanti, MI | Eastern Michigan 76, Detroit Mercy 66 | Box score |
| 11/09/21 | Ypsilanti, MI | Youngstown St. 70, Eastern Michigan 67 | Box score |