| Date | Location | Result | |
| 03-04-22 | Oxford, Ohio (Millett Hall) | Miami (OH) 76, Eastern Michigan 63 | Box score |
| 03-01-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Western Michigan 71, Eastern Michigan 60 | Box score |
| 02-26-22 | Muncie, Ind. (Worthen Arena) | Ball State 75, Eastern Michigan 64 | Box score |
| 02-22-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Eastern Michigan 74, Northern Illinois 72 | Box score |
| 02-19-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Akron 67, Eastern Michigan 48 | Box score |
| 02-17-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Buffalo 83, Eastern Michigan 69 | Box score |
| 02-15-22 | Mount Pleasant, Mich. (McGuirk Arena) | Eastern Michigan 75, Central Michigan 70 | Box score |
| 02-12-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Ohio 74, Eastern Michigan 56 | Box score |
| 02-08-22 | Buffalo, N.Y. (Alumni Arena) | Buffalo 102, Eastern Michigan 64 | Box score |
| 02-05-22 | Kent, Ohio (M.A.C. Center) | Kent State 90, Eastern Michigan 71 | Box score |
| 02-03-22 | Athens, Ohio (Convocation Center) | Ohio 81, Eastern Michigan 68 | Box score |
| 02-01-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Toledo 86, Eastern Michigan 66 | Box score |
| 01-29-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Eastern Michigan 85, Miami (OH) 75 | Box score |
| 01-25-22 | Bowling Green, Ohio (Stroh Center) | Bowling Green 85, Eastern Michigan 71 | Box score |
| 01-22-22 | Akron, Ohio (James A. Rhodes Arena) | Akron 46, Eastern Michigan 44 | Box score |
| 01-18-22 | Ypsilanti, Mich. (Gervin GameAbover Ctr) | Kent State 56, Eastern Michigan 47 | Box score |
| 01-15-22 | DeKalb, Ill. (Convocation Center) | Northern Illinois 77, Eastern Michigan 70 | Box score |
| 01-11-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Eastern Michigan 99, Central Michigan 68 | Box score |
| 01-08-22 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Ball State 78, Eastern Michigan 72 | Box score |
| 01-04-22 | Kalamazoo, Mich. (University Arena) | Eastern Michigan 85, Western Michigan 79 | Box score |
| 12-20-21 | Valparaiso, Ind. (ARC) | Valparaiso 67, Eastern Michigan 55 | Box score |
| 12-11-21 | Ypsilanti, Mich. (Gervin GameAbove Ctr) | Eastern Michigan 92, Florida International 88 (4OT) | Box score |
| 12-08-21 | Ypsilanti, Mich. (Convocation Center) | Eastern Michigan 60, Niagara 58 | Box score |
| 12-05-21 | Ypsilanti, Mich. (Convocation Center) | Eastern Michigan 79, Northwood 57 | Box score |
| 12-02-21 | San Diego, Calif. (RIMAC Arena) | UC San Diego 83, Eastern Michigan 74 | Box score |
| 11-28-21 | Chicago, Ill. (Wintrust Arena) | DePaul 101, Eastern Michigan 63 | Box score |
| 11-24-21 | Ypsilanti, Mich. (Convocation Center) | Eastern Michigan 72, Western Illinois 68 | Box score |
| 11-20-21 | East Lansing, Mich. (Breslin Center) | Michigan State 83, Eastern Michigan 59 | Box score |
| 11-18-21 | Highland Heights, Ky. (BB&T Arena) | Northern Kentucky 74, Eastern Michigan 73 | Box score |
| 11-12-21 | Ypsilanti, Mich. (Convocation Center) | Eastern Michigan 103, Illinois State 98 (2OT) | Box score |
| 11-09-21 | Bloomington, Ind. (Assembly Hall) | Indiana 68, Eastern Michigan 62 | Box score |